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. 2018 Mar 19;13:1653–1664. doi: 10.2147/IJN.S159404

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© 2018 Dabrowska et al. This work is published and licensed by Dove Medical Press Limited

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The ultrastructural study of hBM-MSCs labeled with Molday ION.

Notes: The low magnification picture of the entire cell (A), the high magnification of part of cells including cell membrane and both uptaken superparamagnetic iron oxide nanoparticles, as well as membrane invagination in the areas of Molday ION accumulation (B and C). Interestingly, the process of internalization of the superparamagnetic iron oxide nanoparticles is also captured (D). The red arrows indicate superparamagnetic iron oxide nanoparticles.

Abbreviation: hBM-MSCs, human bone marrow mesenchymal stem cells.