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Effect of biotin supplementation on body weight. Three-week-old mice were fed a control or a biotin-supplemented diet for 1 week. Body weight was measured every day. Values are the mean ± SEM. n: Control = 8; supplemented = 9 mice. Circles: control group; squares: biotin-supplemented. Significance was assessed by the two-factor repeated measurements ANOVA (diet, time). SEM, standard error of the mean.
