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. 2018 Jan 3;9(18):14124–14137. doi: 10.18632/oncotarget.23897

Figure 4. Activating AP-1 formation induces XIAP expression.

Figure 4

(A) The RNA expression level of XIAP is downregulated by inhibiting AP-1 formation. The RNA expression level of XIAP was measured by quantitative real time PCR. The expression of c-Fos and c-Jun was knockdowned by siRNAs and their RNA expression levels were validated by quantitative real time PCR. (B) The protein expression level of XIAP is downregulated by inhibiting AP-1 formation. The protein expression level of XIAP was measured by western blot. (C) The RNA expression level of XIAP is upregulated by activating AP-1 formation. The RNA expression level of XIAP was measured by quantitative real time PCR. The over-expression of c-Fos and c-Jun were validated by quantitative real time PCR. (D) The protein expression level of XIAP is upregulated by activating AP-1 formation. The protein expression level of XIAP was measured by western blot.