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. 2018 Jan 3;9(18):14124–14137. doi: 10.18632/oncotarget.23897

Table 5. Determination of IC50 in HepG2 cells.

Anticancer drugs/IC50 Hepg2 μM
Adriamycin 20.77
Adriamycin and JNJ (50 nM) 40.97
IC50 Promotion rate 97.26%

ADR, Adriamycin. Concentration gradient of ADR for MTT is 0.03448, 0.3448, 3.448, 34.48, 103.448, 344.8, 689.65, 1379.31 μM. IC50Promotion rate % = (Adriamycin + JNJ (50 nM)) group IC50value – Adriamycin group IC50 value)*100%/Adriamycin group IC50value. Resistant fold = MCF7/ADR cells IC50value/ MCF7 cells IC50value.