Table 5. Determination of IC50 in HepG2 cells.
Anticancer drugs/IC50 | Hepg2 μM |
---|---|
Adriamycin | 20.77 |
Adriamycin and JNJ (50 nM) | 40.97 |
IC50 Promotion rate | 97.26% |
ADR, Adriamycin. Concentration gradient of ADR for MTT is 0.03448, 0.3448, 3.448, 34.48, 103.448, 344.8, 689.65, 1379.31 μM. IC50Promotion rate % = (Adriamycin + JNJ (50 nM)) group IC50value – Adriamycin group IC50 value)*100%/Adriamycin group IC50value. Resistant fold = MCF7/ADR cells IC50value/ MCF7 cells IC50value.