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(A) Western blot detection of Rho-Kinase and p-MYPT-Thr696 in HPMCs treated with fasudil (25 μmol/l) or Y-27632 (10 μmol/l) 30 min before exposure to AGEs (50 μg/ml). A1) Quantitative analysis of data shown in A. (B) Western blot detection of vimentin, N-cadherin, E-cadherin, FN, α-SMA, and TGF-β. B1) Quantitative analysis of data shown in B. (Data are mean ± SD; *P < 0.05 vs control, #P < 0.05 vs AGEs, n = 3).
