Table 3. AGTR1 A1166C and CKD odds ratios using allele, dominant, and recessive model assumptions.
Model | Total | Asian | White | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
OR | 95% CI | I2 | Egger's test | OR | 95% CI | I2 | Egger's test | OR | 95% CI | I2 | Egger's test | |
Overall analysis | ||||||||||||
Allele (C vs. A) | 1.07 | 0.97–1.18 | 55.2% | 0.367 | 1.18 | 1.01–1.38 | 21.7% | 0.205 | 1.03 | 0.91–1.18 | 65.1% | 0.033 |
Dominant (CC + AC vs AA) | 1.06 | 0.94–1.20 | 51.3% | 0.040 | 1.17 | 1.00–1.36 | 0.0% | 0.060 | 1.02 | 0.87–1.20 | 64.8% | 0.024 |
Recessive (CC vs AA +AC) | 1.26 | 0.96–1.65 | 60.0% | 0.118 | 2.31 | 0.96–5.54 | 77.7% | 0.095 | 1.10 | 0.84–1.44 | 49.2% | 0.657 |
Abbreviations: I2: index of study heterogeneity; Egger's test: p-value of Egger's regression for asymmetry assessment.