Table 4. Spearman's correlations between viral RNA quantity and cytokine levels in virus-infected culture supernatants between 24 and 72 h post-infection.
Cytokine | Viral RNA quantity at 24 h post-infection | Viral RNA quantity at 72 h post-infection | ||||
---|---|---|---|---|---|---|
r | p | FDR | r | p | FDR | |
IL-1β | - 0.061 | 0.762 | 0.050 | 0.438 | 0.022 | 0.025a |
IL-6 | - 0.090 | 0.656 | 0.033 | 0.060 | 0.765 | 0.042 |
IL-8 | 0.073 | 0.718 | 0.042 | - 0.034 | 0.865 | 0.050 |
IFN-γ | 0.175 | 0.383 | 0.025 | 0.305 | 0.122 | 0.033 |
IP-10 | 0.625 | < 0.001 | 0.008a | 0.530 | 0.004 | 0.017a |
TNF-α | 0.478 | 0.012 | 0.017a | 0.683 | < 0.001 | 0.008a |
Abbreviations: FDR, false discovery rate; IFN, interferon; IL, interleukin; IP-10, IFN-γ-induced protein-10; TNF, tumor necrosis factor.
a Indicates a statistically significant FDR when the Benjamini and Hochberg approach for multiple testing correction was applied.