Table 3. Association between perioperative statin and delirium after potential confounding factors.

Statin	OR(95% CI)	p	C-statistic
Unadjusted Model	0.73 (0.50–1.08)	0.113	0.536 (0.493–0.580)
Adjusted Model
Model 1	0.76 (0.52–1.13)	0.181	0.658 (0.610–0.706)
Model 2	0.59 (0.38–0.90)	0.015	0.723 (0.676–0.769)
Model 3	0.54 (0.33–0.87)	0.011	0.745 (0.704–0.792)

Adjusted Model 1: adjusted for operative time, type of surgery, emergency, general anesthesia. Adjusted Model 2: adjusted for model 1 plus hypertension, diabetes mellitus, COPD, chronic renal failure, heart failure, ASA score, anemia, Adjusted Model 3: adjusted for model 2 plus age, smoking, alcohol, preoperative beta-blocker