Table 5. Summary table for gene ontology (GO) enrichments for genes in the top 5% higher number of 45S rDNA contacts in LCLs, K562, and ESC derived cell types.
Shown are the number of genes represented in each GO category. Raw and adjusted P-values are listed. Adjusted P-values (in brackets) were obtained after Benjamini-Hochberg correction. “ESC set” refers to the sum of contacts in ESC and the four ESC derived cell types.
| GO term | GO ID | LCL Gene count |
LCL P-value (adjusted) |
K562 Gene count |
K562 P-value (adjusted) |
ESC set Gene count |
ESC set P-value (adjusted) |
|---|---|---|---|---|---|---|---|
| ribosome | GO:0005840 | 18 | 9E-07 (0.00013) | 13 | 0.001 (0.067) | 9 | 0.058 (0.66) |
| mitochondrion | GO:0005739 | 63 | 1.3E-06 (0.00014) | 50 | 0.004 (0.17) | 45 | 0.035 (0.60) |
| cytosolic large ribosomal subunit | GO:0022625 | 10 | 0.00005 (0.0039) | 6 | 0.027 (0.56) | 7 | 0.007 (0.29) |
| spliceosomal complex | GO:0005681 | 11 | 0.00012 (0.008) | 6 | 0.085 (0.78) | 8 | 0.009 (0.31) |
| nucleolus | GO:0005730 | 39 | 0.00044 (0.021) | 31 | 0.038 (0.64) | 36 | 0.003 (0.16) |