Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Aug 24;16(5):5752–5758. doi: 10.3892/mmr.2017.7356

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Takeda et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Figure 4. — Effect of losartan on the hepatic expression of profibrotic genes. The expression levels of (A) TGF-β and (B) Col1a1 mRNA in the livers of rats in the G2 group were significantly increased when compared with those in the G1 group. Treatment with 30 mg/kg/day losartan significantly suppressed the expression of TGF-β1 and Col1a1 in the liver. The results are presented as the mean ± standard deviation (G1 and G2, n=6; G3, n=10). *P<0.05 and **P<0.01, as indicated. G1, choline-supplemented amino acid diet-fed control rats; G2, CDAA diet-fed rats; G3, losartan-treated CDAA diet-fed rats; CDAA, choline-deficient L-amino acid; CDAA, choline-deficient L-amino acid; TGF, transforming growth factor; Col1a1, collagen type 1 α1.