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. 2017 Aug 24;16(5):5752–5758. doi: 10.3892/mmr.2017.7356

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Copyright: © Takeda et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — Effect of losartan on hepatic periostin expression. The expression of periostin (A) mRNA (B) protein in the livers of rats in the G2 group was significantly increased when compared with rats in the G1 group. Treatment with losartan significantly suppressed the expression of periostin in the liver of rats from the G3 group. The results are presented as the mean ± standard deviation (G1 and G2, n=6; G3, n=10). *P<0.05 and **P<0.01, as indicated. G1, choline-supplemented amino acid diet-fed control rats; G2, CDAA diet-fed rats; G3, losartan-treated CDAA diet-fed rats; CDAA, choline-deficient L-amino acid.