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. 2017 Aug 23;16(5):5779–5786. doi: 10.3892/mmr.2017.7342

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Copyright: © Jia et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — Chloroquine inhibits oral squamous cell carcinoma tumor growth in a CAL27 xenograft nude mouse model. (A) Images of the gross tumors from nude mice treated with chloroquine or normal saline. (B and C) Tumor growth curve represented by the average tumor volumes of CAL27 xenograft nude mice from the control and chloroquine-treated groups. Chloroquine treatment reduced the tumor growth rate in CAL27 xenograft nude mice. (D) Average weights of tumors excised from chloroquine-treated female and male mice were 25.68 and 38.28% lower than control mice, respectively. *P<0.05, **P<0.01 vs. control.