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The expression of RBP4 was downregulated in the EPM treated with atRA. (A) When compared with the Con group, mRNA expression of RBP4 was reduced in the atRA group at E13.5 and E14.5. (B) Protein expression of RBP4 from E12.5 to E14.5 was lower in the atRA groups vs. Con. *P<0.05, **P<0.01 and ***P<0.001. RBP4, retinol binding protein 4; EPM, embryonic palatal mesenchyme; atRA, all-trans retinoic acid; E, embryonic day; Con, control.
