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. 2017 Aug 22;16(5):5915–5923. doi: 10.3892/mmr.2017.7327

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Copyright: © Dong et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — atRA suppressed RBP4 mRNA levels and altered the mRNA levels of p27 and cyclin D1 in human embryonic palatal mesenchymal cells. (A) mRNA expression of RBP4 was decreased in the atRA-treated group compared with that in the Con group. (B) mRNA expression of p27 was increased in the atRA-treated group compared with the Con group. (C) mRNA expression of cyclin D1 was reduced in the atRA-treated group compared with the Con group. There were 3 duplicate cultures in each group, and experiments were performed in triplicate. *P<0.05, **P<0.01 and ***P<0.001. atRA, all-trans retinoic acid; RBP4, retinol binding protein 4; Con, control.