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. 2017 Aug 22;16(5):5915–5923. doi: 10.3892/mmr.2017.7327

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Copyright: © Dong et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — Knockdown of RBP4 induced upregulation of p27 and downregulation of cyclin D1 at the mRNA level. (A) When compared with the Con group, RBP4 mRNA levels were downregulated in HEPM cells treated with RBP4 siRNA. (B) P27 mRNA levels were upregulated in HEPM cells treated with RBP4 siRNA via Con. (C) Cyclin D1 mRNA levels were downregulated in HEPM cells treated with RBP4 siRNA compared with Con. A total of 3 duplicate samples were used in each group, and experiments were performed in triplicate. *P<0.05, **P<0.01 and ***P<0.001. RBP4, retinol binding protein 4; HEPM, human embryonic palatal mesenchymal; siRNA, small interfering RNA; Con, control siRNA.