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. 2017 Aug 22;16(5):6034–6040. doi: 10.3892/mmr.2017.7319

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Copyright: © Qian et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — IRF4 is up-regulated in human NSCLC (A) IRF4 mRNA level is overexpressed in human non-small cell lung cancer (NSCLC) tissues (T) compared with non-tumor adjacent normal tissues (N) (n=54 in each group). (B) IRF4 protein level is up-regulated in NSCLC tissues (T) compared with non-tumor adjacent normal tissues (N) (n=54 in each group). Representative western blot images were shown (n=5, 1case (lane 1) with adenocarcinoma and 4 cases (lane 2–5) with squamous cell carcinoma). (C) Quantitative results of IRF4 protein level in (B). The protein level of IRF4 is normalized by GAPDH protein level. N=54 in each group. 54 NSCLC cases consist of 22 cases with adenocarcinoma and 32 cases with squamous cell carcinoma. IRF4, interferon regulatory factor 4; NSCLC, non-small cell lung cancer; T, tumor; N, non-tumor.