Table III.

KEGG pathways of the modules in the present study.

A, Module A
KEGG pathways	Genes	P-value
hsa04114: Oocyte meiosis	CCNB2, CCNB1, PLK1, AURKA	1.59×10−6
hsa04914: Progesterone-mediated oocyte maturation	CCNB2, CCNB1, PLK1	4.49×10−5
hsa04110: Cell cycle	CCNB2, CCNB1, PLK1	8.87×10−5
hsa04068: FoxO signaling pathway	CCNB2, CCNB1, PLK1	1.11×10−4
hsa04115: p53 signaling pathway	CCNB2, CCNB1	1.10×10−3
B, Module B
KEGG pathways	Genes	P-value
hsa04080: Neuroactive ligand-receptor interaction	CHRM2, SSTR1, F2R, TACR1, C5AR1, S1PR4	5.31×10−6
hsa04024: cAMP signaling pathway	CHRM2, SSTR1, NPY, RGS2, FFAR2	1.70×10−5
hsa04020: Calcium signaling pathway	GNA14, CHRM2, TACR1, F2R	2.02×10−4
hsa04610: Complement and coagulation cascades	C5AR1, F2R	7.29×10−3
hsa04810: Regulation of actin cytoskeleton	CHRM2, F2R	4.61×10−3
hsa04151: PI3K-Akt signaling pathway	CHRM2, F2R	1.03×10−2
C, Module C
KEGG pathways	Genes	P-value
hsa04115: p53 signaling pathway	RRM2, CCNG2, CDKN2A, CCNE2	5.94×10−6
hsa04110: Cell cycle	CDC25B, CDKN2A, CDC25A, CCNE2	5.46×10−5
hsa05206: MicroRNAs in cancer	CDC25B, CDKN2A, CDC25A, CCNE2	1.44×10−3
hsa04914: Progesterone-mediated oocyte maturation	CDC25A, CDC25B	1.14×10−2
hsa04068: FoxO signaling pathway	PLK2, CCNG2	2.05×10−2
hsa05203: Viral carcinogenesis	CDKN2A, CCNE2	4.42×10−2
D, Module D
KEGG pathways	Genes	P-value
hsa05166: HTLV-I infection	EGR2, WNT5A, WNT5B, NFATC2	1.11×10−3
hsa04310: Wnt signaling pathway	WNT5A, WNT5B, NFATC2	2.08×10−3
hsa05161: Hepatitis B	EGR2, STAT6, NFATC2	2.20×10−3
hsa04360: Axon guidance	WNT5A, WNT5B, NFATC2	3.70×10−3
hsa05217: Basal cell carcinoma	WNT5A, WNT5B	4.41×10−3
hsa04916: Melanogenesis	WNT5A, WNT5B	1.36×10−2
hsa04550: Signaling pathways regulating pluripotency of stem cells	WNT5A, WNT5B	2.59×10−2
hsa04390: Hippo signaling pathway	WNT5A, WNT5B	3.00×10−2
hsa04150: mTOR signaling pathway	WNT5A, WNT5B	3.01×10−2
hsa05205: Proteoglycans in cancer	WNT5A, WNT5B	5.00×10−2

KEGG, Kyoto Encyclopedia of Genes and Genomes.