Table IV.

Enriched GO functions for the DEGs.

A, Biological processes
GO Term	Function	Count	FDR	Examples of DEGs
GO:0000280	Nuclear division	31	3.83×10−6	CCNB1, CCNB2, PLK1, AURKB, CCNG2
GO:0007067	Mitosis	31	3.97×10−6	KIF23, CCNA2, CCNB2, PLK1, CDCA2
GO:0000087	M phase of mitotic cell cycle	31	5.90×10−6	KIF23, KIFC1, KIF22, NEK2, HAUS1
GO:0000278	Mitotic cell cycle	41	8.90×10−6	CDKN1A, CCNB2, PLK2, PLK1, RNF2
GO:0048285	Organelle fission	31	9.98×10−6	NDC80, UBE2C, CDC25A, CCNB1, CCNB2
GO:0022403	Cell cycle phase	42	7.08×10−5	BCAT1, KIF23, KIF22, KIFC1, PRC1
GO:0051301	Cell division	34	9.05×10−5	CCNE2, SPC25, NDE1, CDKN2A, NCAPG
GO:0000279	M phase	36	1.25×10−4	CCNA2, ERCC6L, KIF11, DLGAP5, NUF2
GO:0007049	Cell cycle	61	4.66×10−4	CCNB2, PLK2, RGS2, MAPK13, PLK1
GO:0022402	Cell cycle process	48	1.36×10−3	BCAT1, KIF23, KIF22, KIFC1, PRC1
GO:0009101	Glycoprotein biosynthetic process	22	1.56×10−3	GALNT3, ST6GAL1, ST6GAL2, LDLR, FUT8
GO:0009100	Glycoprotein metabolic process	24	7.23×10−3	GALNT3, ST6GAL1, ST8SIA1, CHST3, ABCG1
GO:0043413	Biopolymer glycosylation	18	1.72×10−2	GALNT3, ST6GAL1, ABCG1, MPDU1, B3GNT3
GO:0006486	Protein amino acid glycosylation	18	1.73×10−2	COG7, ST3GAL4, B3GNT7, ST3GAL6, MPDU1
GO:0070085	Glycosylation	18	1.73×10−2	GALNT3, ST6GAL1, ST6GAL2, ALG1, ST3GAL1
GO:0055114	Oxidation reduction	23	3.15×10−2	DHRS9, ACADL, GMPR, ALDH1A1, AKR1C3
B, Cellular components
Term	Function	Count	FDR	Examples of DEGs
GO:0005819	Spindle	20	5.53×10−3	KIF23, NDE1, APP, PLK1, SKA1
GO:0000779	Condensed chromosome, centromeric region	13	1.02×10−2	CENPN, NUF2, CENPF, NDC80, AURKB
GO:0000793	Condensed chromosome	18	1.36×10−2	CENPN, NEK2, SKA1, CENPF, CHEK1,
GO:0000777	Condensed chromosome kinetochore	12	1.61×10−2	SPC25, CENPN, NDE1, CENPA, NUF2,
GO:0005624	Membrane fraction	56	4.37×10−2	NPR3, RGS16, CCNB2, APP, CHRM2
GO:0000776	Kinetochore	13	4.48×10−2	KIF22, CENPN, NUF2, CENPF, CENPK
GO:0005626	Insoluble fraction	56	4.12×10−2	CYP2J2, CADM1, CCNB2, NPR3, RGS16
C, Molecular functions
Term	Function	Count	FDR	Examples of DEGs
GO:0008373	Sialyltransferase activity	7	4.14×10−2	ST6GAL1, ST6GAL2, ST3GAL4, ST3GAL6
GO:0016229	Steroid dehydrogenase activity	4	1.89×10−2	AKR1C3, HSD11B2, DHRS9, HSD17B6
GO:0050327	Testosterone 17-beta-dehydrogenase activity	2	2.62×10−2	AKR1C3, HSD17B6

GO, gene ontology; FDR, false discovery rate; DEGs, differentially expressed genes.