Table I.

Cell grouping and treatments.

Groups	Treatment reagent	Description
Control	Medium	Treated with control medium
4-PBA	4-PBA	Treated with 4-PBA at concentration of 0.6 mmol/l
siRNA	siRNA	Specific siRNA against IRAK2
d-flow	d-flow	Artificial d-flow model
d-flow+IL-1Ra	IL-1Ra and d-flow	Treated with IL-1Ra at concentration of 200 ng/ml when exposed to d-flow
d-flow+4PBA	4-PBA and d-flow	Treated with 4-PBA when exposed to d-flow
d-flow+siRNA	siRNA and d-flow	Pretreated with siRNA against IRAK2 and subse quently exposed to d-flow

4-PBA, 4-phenylbutyric acid; d-flow, disturbed blood flow; siRNA, small interfering RNA; IL-1Ra, interleukin-1 receptor antagonist protein.