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. 2017 Sep 21;16(5):7229–7236. doi: 10.3892/mmr.2017.7569

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Copyright: © Ji et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Effect of DhHP-6 on neuronal apoptosis of the ischemic cortex in rats 22 h post-reperfusion. (A) TUNEL staining was used to identify apoptotic cells in the parietal cortex. Arrows indicate TUNEL-positive cells (magnification, ×200). (B) As demonstrated in the bar graphs, the apoptotic index indicates the percentage of TUNEL-positive cells in the ischemic cortex. The percentage of TUNEL-positive cells in the I/R+DH group was significantly lower, compared with that in the I/R group. Data are demonstrated as the mean ± standard deviation. One-way analysis of variance and Tukey's post hoc test were performed. ^###P<0.001, vs. Sham group; *P<0.05, vs. I/R group (n=5). DhHP-6, deuterohemin His peptide-6; DH, 1 mg/kg/day DhHP-6; DL, 0.1 mg/kg/day DhHP-6.