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. 2017 Sep 19;16(5):7382–7390. doi: 10.3892/mmr.2017.7511

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Copyright: © Jiang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Interaction network of 18 macrophage polarization-associated genes as identified by STRING analysis. The results were expanded to the current network by setting the required confidence score to 0.400. The nodes represent the genes, whereas the lines represent interactions between genes. The color of the line denotes the basis of the predicted interaction according to the software database. STRING, Search Tool for the Retrieval of Interacting Genes; Retnla, resistin-like α; Chi3l3, chitinase 3-like 3; Mrc1, mannose receptor C-type 1; Arg1, arginase 1; Nostrin, nitric oxide synthase trafficker; Nos2, nitric oxide synthase 2; Hif1, hypoxia-inducible factor 1; Tnf, tumor necrosis factor; Ccl24, C-C motif chemokine ligand 24; Il, interleukin; Socs, suppressor of cytokine signaling; Irak2, interleukin 1 receptor associated kinase 2; Pparg, peroxisome proliferator-activated receptor.