Table IV.
Top 5 Kyoto Encyclopedia of Genes and Genomes pathways of upregulated and downregulated differentially expressed genes.
| Category | Term | Gene count | P-value |
|---|---|---|---|
| Up | hsa04610:Complement and coagulation cascades | 9 | 1.59×10−05 |
| Up | hsa04062:Chemokine signaling pathway | 13 | 5.37×10−05 |
| Up | hsa04512:ECM-receptor interaction | 8 | 4.55×10−04 |
| Up | hsa04060:Cytokine-cytokine receptor interaction | 13 | 1.231×10−03 |
| Up | hsa04621:NOD-like receptor signaling pathway | 6 | 3.553×10−03 |
| Down | hsa00910:Nitrogen metabolism | 3 | 2.866×10−03 |
| Down | hsa00830:Retinol metabolism | 3 | 1.519×10−02 |
| Down | hsa00980:Metabolism of xenobiotics by cytochrome P450 | 3 | 1.8555×10−02 |
| Down | hsa00982:Drug metabolism | 3 | 1.9741×10−02 |
| Down | hsa03320:PPAR signaling pathway | 3 | 2.4136×10−02 |
ECM, extracellular matrix; NOD, nucleotide-binding oligomerization domain; PPAR, peroxisome proliferator-activated receptor.