Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Feb 1;17(4):4899–4908. doi: 10.3892/mmr.2018.8535

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Figure 3. — Mechanism of MTA2-mediated signaling pathways in non-small cell lung carcinoma cells. (A) E-cadherin, Snail, N-cadherin and vimentin expression levels in A549 cells following treatment with the indicated agents. (B) ERK and AKT expression in A549 cells following treatment with the indicated agents. (C) Apoptosis-associated proteins caspase-3 and Bad expression levels in A549 cells. (D) VEGFR1, VEGFR2 and VEGFR3 expression levels in AbMTA2-treated A549 cells. (E) VEGF and EGF expression levels in AbMTA2-treated A549 cells. (F) Ep-CAM and TAF expression in A549 cells. The data are presented as the mean ± standard error of the mean of three independent experiments. **P<0.01 vs. control. MTA2, metastasis associated protein MTA2; Snail, zinc-finger protein SNAI1; ERK, extracellular signal-regulated kinase; AKT, RAC-α serine/threonine protein kinase; Bad, Bcl2-associated agonist of cell death; VEGFR, vascular endothelial growth factor receptor; EGF, pro-epidermal growth factor; Ep-CAM, epithelial cell adhesion molecule; TAF, tumor angiogenesis factor; si, small interfering; Ab, antibody.