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. 2018 Jan 24;17(4):5007–5012. doi: 10.3892/mmr.2018.8477

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Copyright: © Wu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — Changes in HMGB1, JAK2, p-JAK2, STAT3, and p-STAT3 expression in brain tissue of rats after cerebral ischemia. Sham group and MCAO group, 3 rats in each group. The brain tissues were harvested 24 h after operation and change of HMGB1, JAK2, p-JAK2, STAT3, and p-STAT3 contents in the cerebral tissue homogenate was measured using western blotting. (A) Protein bands of cerebral tissue homogenate; (B) Relative expression of the target protein in the homogenate of brain tissue was calculated using the ImageJ image analysis software (Bethesda, MD, USA) (**P<0.01, *P<0.05).