Figure 4.

Effects of MRS and NRS on Aβ (1–42)-induced nuclear factor-κB p65 activity. The BV-2 cells were pretreated with 10% MRS or NRS for 1 h, followed by co-treatment with 5 µM Aβ (1–42) for another 4 h. The extracts from cell cultures were prepared and analyzed. Each value indicates the mean ± standard deviation from three independent experiments. ^#P<0.01, vs. untreated control cells. *P<0.05, vs. cells treated with Aβ (1–42) alone. MRS, medicated rat serum containing Gengnianchun formula; NRS, non-medicated rat serum; Aβ, amyloid β; p-, phosphorylated.