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PADI4 expression in FLS. Post-transfection of (A) N-FLS with Ad-PADI4 and (B) RA-FLS with sh-PADI4, the mRNA expression levels of PADI4 were measured by reverse transcription-quantitative polymerase chain reaction. Data represent three independent experiments with presented as mean ± standard deviation. *P<0.01. Ad, adenovirus; FLS, fibroblast-like synoviocytes; PADI4, peptidyl arginine deiminase type IV; RA, rheumatoid arthritis; sh, short hairpin RNA.
