Table IV.
Associated pathways of the potential targets of Bufei Yishen formula.
| Term | Count | % | P-value |
|---|---|---|---|
| Neuroactive ligand-receptor interaction | 30 | 0.7413 | P<0.0001 |
| Amyotrophic lateral sclerosis | 12 | 0.2965 | P<0.0001 |
| Pathways in cancer | 27 | 0.6672 | P<0.0001 |
| Drug metabolism | 12 | 0.2965 | P<0.0001 |
| Calcium signaling pathway | 19 | 0.4695 | P<0.0001 |
| Bladder cancer | 10 | 0.2471 | P<0.0001 |
| Metabolism of xenobiotics by cytochrome P450 | 11 | 0.2718 | P<0.0001 |
| Non-small cell lung cancer | 10 | 0.2471 | P<0.0001 |
| Glutathione metabolism | 9 | 0.2224 | 0.0001 |
| Colorectal cancer | 11 | 0.2718 | 0.0001 |
| Small cell lung cancer | 11 | 0.2718 | 0.0001 |
| Pancreatic cancer | 10 | 0.2471 | 0.0001 |
| Prostate cancer | 11 | 0.2718 | 0.0001 |
| Vascular endothelial growth factor signaling pathway | 10 | 0.2471 | 0.0002 |
| Gap junction | 10 | 0.2471 | 0.0007 |
| Thyroid cancer | 6 | 0.1483 | 0.001 |
| Focal adhesion | 15 | 0.3706 | 0.0011 |
| Gonadotropin-releasing hormone signaling pathway | 10 | 0.2471 | 0.0013 |
| Glioma | 8 | 0.1977 | 0.0015 |
| Alzheimer's disease | 13 | 0.3212 | 0.0015 |
| Progesterone-mediated oocyte maturation | 9 | 0.2224 | 0.0022 |
| Prion diseases | 6 | 0.1483 | 0.0024 |
| T cell receptor signaling pathway | 10 | 0.2471 | 0.0026 |
| Arginine and proline metabolism | 7 | 0.173 | 0.003 |
| Melanoma | 8 | 0.1977 | 0.003 |
| Fc epsilon RI signaling pathway | 8 | 0.1977 | 0.0051 |
| Toll-like receptor signaling pathway | 9 | 0.2224 | 0.0061 |
| Neurotrophin signaling pathway | 10 | 0.2471 | 0.0065 |
| Nucleotide-binding oligomerization domain-like receptor signaling pathway | 7 | 0.173 | 0.0065 |
| Apoptosis | 8 | 0.1977 | 0.0093 |
| Adipocytokine signaling pathway | 7 | 0.173 | 0.0095 |
| Vascular smooth muscle contraction | 9 | 0.2224 | 0.0111 |
| Insulin signaling pathway | 10 | 0.2471 | 0.0111 |
| Renal cell carcinoma | 7 | 0.173 | 0.0117 |
| Endometrial cancer | 6 | 0.1483 | 0.0132 |
| Mitogen-activated protein kinase signaling pathway | 15 | 0.3706 | 0.0137 |
| Caffeine metabolism | 3 | 0.0741 | 0.0142 |
| B cell receptor signaling pathway | 7 | 0.173 | 0.0161 |
| Arachidonic acid metabolism | 6 | 0.1483 | 0.0178 |
| Graft-versus-host disease | 5 | 0.1235 | 0.021 |
| Phenylalanine metabolism | 4 | 0.0988 | 0.021 |
| Tryptophan metabolism | 5 | 0.1235 | 0.0228 |
| Oocyte meiosis | 8 | 0.1977 | 0.0302 |
| ErbB signaling pathway | 7 | 0.173 | 0.031 |
| Tyrosine metabolism | 5 | 0.1235 | 0.0312 |
| p53 signaling pathway | 6 | 0.1483 | 0.0374 |
| Epithelial cell signaling in Helicobacter pylori infection | 6 | 0.1483 | 0.0374 |
| Type II diabetes mellitus | 5 | 0.1235 | 0.0385 |
| Complement and coagulation cascades | 6 | 0.1483 | 0.0395 |