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. 2018 Feb 21;17(4):5684–5691. doi: 10.3892/mmr.2018.8624

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Copyright: © Zhou et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Effects of CBX treatment on brain edema, integrity and active-caspase-3 level following ICH. (A) Brain water content was measured by the wet/dry weight method at 48 h post-ICH. (B) The effects of CBX treatment on BBB integrity and neuronal apoptosis post-ICH were detected by the protein expression levels of albumin and active-caspase-3. Quantitative analyses of the relative protein levels of (C) albumin and (D) active-caspase-3. The mean band intensity of the sham group was normalized to 1.0. Data are presented as the mean ± standard error of the mean. *P<0.05 vs. sham group; ^#P<0.05 vs. ICH group; ^##P<0.01 vs. ICH group; n=6/group. BBB, blood-brain barrier; CBX, carbenoxolone; H, high; ICH, intracerebral hemorrhage; L, low.