Figure 4.

Ki67 immunoreactivity in the dentate gyrus of (A) euthyroid and (B) hypothyroid rats. Ki67 positive nuclei are identified in the subgranular zone of dentate gyrus. There are fewer Ki67 positive nuclei in the hypothyroid group than in the euthyroid group. Scale bar, 100 µm. (C) Number of Ki67-positive nuclei per section for each group. Differences between the means were analyzed using Student's t-test (n=5 per group; *P<0.05 vs. euthyroid). The bars represent the mean ± standard error of the mean. GCL, granule cell layer; ML, molecular layer; PL, polymorphic layer.