Figure 5.

DCX immunoreactivity in the dentate gyrus of (A) euthyroid and (B) hypothyroid rats. DCX immunoreactive neuroblasts are present in the subgranular zone of dentate gyrus (cytoplasm) and their dendrites are extended into the ML of the dentate gyrus. There are fewer DCX immunoreactive neuroblasts and their dendrites in the hypothyroid rats compared with the euthyroid rats. Scale bar, 100 µm (left) and 50 µm (right). (C) Number of DCX-immunoreactive neuroblasts per section for each group. Differences between the means were analyzed using Student's t-test (n=5 per group; *P<0.05 vs. euthyroid). The bars represent the mean ± standard error of means. DCX, doublecortin; ML, molecular layer; GCL, granule cell layer; PL, polymorphic layer.