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. Author manuscript; available in PMC: 2018 Mar 23.
Published in final edited form as: Am J Ophthalmol. 2017 Dec 30;187:51–60. doi: 10.1016/j.ajo.2017.12.017

FIGURE 2.

FIGURE 2

Varicella-zoster virus (VZV) positivity in temporal artery biopsies. Examples of immunohistochemistry-positive results from 3 giant cell arteritis (GCA)-positive patients. The top row includes samples examined by wet mount; the center and bottom rows contain samples examined by dry mount at 2 magnifications. Zoster antigen was detected with monoclonal antibody 3B3 against major zoster protein E (gE) and appears as darker stained areas indicated by white arrows in the top row (wet mounts) and by black arrows in the center and bottom rows (dry mounts). Case #3 shows VZV-positive staining located in a branch artery off the main vessel (asterisk). Case #7 (center row) shows VZV-positive staining located mainly in the medial layer. Case #8 shows VZV-positive staining located in the intimal, medial and adventitial layers. Scale bars are shown in each image.