Table 4. Univariate and multivariable models comparing OSA risk based on STOP-BANG scores and BMI>35kg/m²by VMS severity.

Analysis adjusted for age, BMI, and smoking status.

	Univariate Analysis					Multivariable Analysis (using none/mild vs Moderate/severe/very severe)			Multivariable Analysis (using none/mild/moderate vs Severe/very severe)
	Intermediate/High OSA Risk (N=421) Mean (SD)	Low OSA Risk (N=1270) Mean (SD)	Odds Ratio	95% CI	p value	Odds Ratio	95% CI	p-value	Odds Ratio	95% CI	p-value
Age	54.6 (6.2)	52.9 (6.2)	1.05	(1.03, 1.07)	<0.001	1.05	(1.03, 1.08)	<0.001	1.06	(1.03, 1.08)	<0.001
BMI	31.0 (7.1)	25.4 (4.9)	1.17	(1.14, 1.20)	<0.001	1.17	(1.14, 1.20)	<0.001	1.17	(1.14, 1.20)	<0.001
Smoking Status, N (%)
Never	278 (23.0%)	932 (77.0%)	Reference			Reference			Reference
Former	105 (29.9%)	246 (70.1%)	1.43	(1.10, 1.87)	0.42	1.10	(0.77, 1.58)	0.34	1.12	(0.78, 1.61)	0.41
Current	24 (31.6%)	52 (68.4%)	1.55	(0.94, 2.56)	0.31	1.88	(0.97, 3.66)	0.084	1.83	(0.94, 3.59	0.11
Hypertensiona, N (%)
No	244 (17.1%)	1181 (82.9%)	Reference			Reference			Reference
Yes	176 (67.4%)	85 (32.6%)	10.02	(7.47, 13.44)	<0.001	8.23	(5.71, 11.85)	<0.001	8.34	(5.78, 12.0)	<0.001
MRS Total	16.8 (8.0)	12.9 (7.0)	1.07	(1.05, 1.09)	<0.001
VMSb, N (%)
None/Mild	202 (21.5%)	738 (78.5%)	Reference			Reference
Moderate/severe/very severe	219 (29.2%)	532 (70.8%)	1.54	(1.23, 1.93)	<0.001	1.34	(0.99, 1.81)	0.063
VMSb, N (%)
None/Mild/Moderate	309 (22.3%)	1079 (77.7%)	Reference						Reference
Severe/very severe	112 (37.0%)	191 (63.0%)	2.15	(1.64, 2.81)	<0.001				1.87	(1.29, 2.71)	<0.001

^aHypertension as self-reported on STOP-BANG

^bVasomotor symptoms (VMS): hot flashes and night sweats