Table 5. Univariate and multivariable models comparing OSA risk based on STOP-BANG scores and BMI>35kg/m2 by VMS severity: BMI subgroup analysis.
BMI subgroup analysis adjusted for age and smoking status.
|
BMI < 25
| |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Univariate Analysis | Multivariable Analysis (using none/mild vs Moderate/severe/very severe) | Multivariable Analysis (using none/mild/moderate vs Severe/very severe) | |||||||||
|
| |||||||||||
| Intermediate/High OSA Risk (N=64) Mean (SD) | Low OSA Risk (N=569) Mean (SD) | Odds Ratio | 95% CI | p value | Odds Ratio | 95% CI | p-value | Odds Ratio | 95% CI | p-value | |
| Age | 55.1 (5.1) | 53.2 (6.2) | 1.05 | (1.01, 1.10) | 0.031 | 1.05 | (1.004, 1.10) | 0.034 | 1.06 | (1.01, 1.11) | 0.024 |
| Smoking Status, N (%) | |||||||||||
| Never | 49 (10.4%) | 423 (89.6%) | Reference | Reference | Reference | ||||||
| Former | 12 (10.6%) | 101 (89.4%) | 1.03 | (0.53, 2.00) | 0.35 | 0.94 | (0.48, 1.85) | 0.47 | 0.93 | (0.47, 1.82) | 0.46 |
| Current | 1 (3.8%) | 25 (96.2%) | 0.35 | (0.05, 2.61) | 0.30 | 0.37 | (0.05, 2.83) | 0.35 | 0.36 | (0.05, 2.72) | 0.34 |
| MRS Total | 15.3 (7.9) | 12.9 (6.9) | 1.04 | (1.004, 1.08) | 0.028 | ||||||
| VMSa, N (%) | |||||||||||
| None/Mild | 36 (9.4%) | 346 (90.6%) | Reference | Reference | |||||||
| Moderate/severe/very severe | 28 (11.2%) | 223 (88.8%) | 1.12 | (0.66, 1.91) | 0.67 | 1.22 | (0.71, 2.09) | 0.47 | |||
| VMSa, N (%) | |||||||||||
| None/Mild/Moderate | 50 (9.2%) | 495 (90.8%) | Reference | Reference | |||||||
| Severe/very severe | 14 (15.9%) | 74 (84.1%) | 1.90 | (0.999, 3.62) | 0.051 | 2.15 | (1.12, 4.16) | 0.022 | |||
|
BMI ≥ 25
| |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Univariate Analysis | Multivariable Analysis (using none/mild vs Moderate/severe/very severe) | Multivariable Analysis (using none/mild/moderate vs Severe/very severe) | |||||||||
|
| |||||||||||
| Intermediate/High OSA Risk (N=264) Mean (SD) | Low OSA Risk (N=471) Mean (SD) | Odds Ratio | 95% CI | p value | Odds Ratio | 95% CI | p-value | Odds Ratio | 95% CI | p-value | |
| Age | 54.5 (5.8) | 53.0 (6.3) | 1.04 | (1.02, 1.07) | <0.001 | 1.05 | (1.02, 1.08) | <0.001 | 1.05 | (1.02, 1.08) | <0.001 |
| Smoking Status, N (%) | |||||||||||
| Never | 171 (33.9%) | 334 (66.1%) | Reference | Reference | Reference | ||||||
| Former | 67 (38.3%) | 108 (61.7%) | 1.21 | (0.85, 1.73) | 0.23 | 1.15 | (0.80, 1.65) | 0.14 | 1.15 | (0.80, 1.66) | 0.15 |
| Current | 21 (56.8%) | 16 (43.2%) | 2.56 | (1.30, 5.04) | 0.014 | 2.66 | (1.33, 5.31) | 0.010 | 2.62 | (1.31, 5.25) | 0.012 |
| MRS Total | 17.2 (8.2) | 12.6 (7.0) | 1.08 | (1.06, 1.11) | <0.001 | ||||||
| VMSa, N (%) | |||||||||||
| None/Mild | 120 (31.3%) | 264 (68.8%) | Reference | Reference | |||||||
| Moderate/severe/very severe | 144 (41.0%) | 207 (59.0%) | 1.59 | (1.17, 2.17) | 0.003 | 1.61 | (1.18, 2.20) | 0.003 | |||
| VMSa, N (%) | |||||||||||
| None/Mild/Moderate | 189 (32.7%) | 389 (67.3%) | Reference | Reference | |||||||
| Severe/very severe | 75 (47.8%) | 82 (52.2%) | 2.01 | (1.40, 2.90) | <0.001 | 2.03 | (1.39, 2.94) | <0.001 | |||
a
Vasomotor symptoms (VMS): hot flashes and night sweats