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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Biochim Biophys Acta. 2018 Feb 2;1862(5):1069–1078. doi: 10.1016/j.bbagen.2018.01.020

Figure 7. FcεRI and gp130 signals synergize to enhance STAT3 phosphorylation in human skin mast cells.

Figure 7

Western blot showing phosphorylation of STAT3 at tyrosine 705 and serine 727. Human skin mast cells were sensitized with anti-NP IgE, and then treated with IL-6 (100 ng/ml), NP-BSA (100 ng/ml), or IL-6 + NP for 15 min. STAT3 phosphorylation was determined by SDS-PAGE and Western blot analysis of whole cell lysates. Blot is representative of two separate experiments with mast cells from different donors.