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. 2018 Feb 25;7(5):e005052. doi: 10.1161/JAHA.116.005052

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© 2018 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Neovascularization around ischemic foci after cerebral ischemia/reperfusion in mice. A, Schematic drawing of ischemic foci and the infarction border zone (IBZ) after cerebral ischemia/reperfusion in mice. B, Compared with the sham‐operated control group, the number of CD31‐stained vascular endothelial cells around the ischemic foci increased significantly 3 and 7 days after middle cerebral artery occlusion/reperfusion in the treated mouse group; this number gradually increased with time after ischemia/reperfusion (n=6, **P<0.01). d indicates days; DAPI, 4′,6‐diamidino‐2‐phenylindole.