Table 4.

Cutoff Points of cTnT

Cutoff, ng/L	No. of Operations				Sensitivity, %	Specificity, %	LR+	LR−	Posttest Probability, %
	TP	FN	TN	FP
MACCE
Conventional cTnT
200	70	22	393	264	72	60	1.78	0.48	19
400	38	54	569	88	42	87	3.34	0.66	31
600	22	70	625	32	28	94	5.03	0.76	41
800	16	76	639	18	19	97	7.30	0.84	50
1000	12	80	648	9	13	99	9.74	0.88	57
1200	12	80	653	4	10	99	12.81	0.91	64
1400	9	83	654	3	7	100	15.52	0.93	68
High‐sensitivity cTnT
200	108	6	193	666	95	22	1.21	0.22	14
400	76	38	604	255	68	71	2.33	0.45	24
600	53	61	771	88	43	89	4.11	0.63	36
800	39	75	825	34	26	96	6.83	0.77	48
1000	26	88	843	16	18	98	9.89	0.84	57
1200	19	95	850	9	13	99	12.75	0.88	63
1400	11	103	854	5	10	99	15.40	0.90	68
Safety composite
Conventional cTnT
200	94	52	363	240	62	60	1.57	0.62	25
400	50	96	527	76	35	88	3.06	0.73	39
600	30	116	579	24	23	95	5.03	0.80	51
800	23	123	592	11	15	98	8.44	0.87	64
1000	15	131	597	6	10	99	12.70	0.90	73
1200	14	132	601	2	7	100	19.27	0.93	80
1400	11	135	602	1	5	100	26.28	0.95	85
High‐sensitivity cTnT
200	144	9	190	630	93	22	1.19	0.34	20
400	92	61	581	239	63	72	2.22	0.52	32
600	64	89	743	77	40	90	4.01	0.67	46
800	45	108	792	28	24	97	7.00	0.79	60
1000	29	124	807	13	16	98	10.59	0.85	69
1200	22	131	814	6	11	99	15.32	0.90	76
1400	13	140	817	3	8	100	20.55	0.92	81

Sensitivity, specificity, and posttest probability are fitted. Fitted posttest probability of a positive test corresponds to the positive predictive value. cTnT indicates cardiac troponin T; FN, false negative; FP, false positive; LR⁺, fitted positive likelihood ratio that corresponds to a troponin value above the cutoff; LR⁻, fitted negative likelihood ratio for a troponin value below or equal to the cutoff; MACCE, major adverse cardiac or cerebrovascular event; TN, true negative; and TP, true positive.