Figure 1.

Milestones in SUNDS. It has been 100 years since the first description of SUNDS in 1917 in Philippines. There were 2 major active periods of studies on SUNDS: The early stage mainly focused on collecting the epidemiological characteristics and revealing the probable external environmental risk factors; the later stage was aimed at uncovering the intrinsic gene susceptibility. BrS indicates Brugada Syndrome; CCS, cardiac conduction system; CDC, Centers for Disease Control and Prevention; SUNDS, sudden unexplained nocturnal death syndrome; US, the United States; VF, ventricular fibrillation.