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. 2018 Mar 3;7(5):e008268. doi: 10.1161/JAHA.117.008268

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© 2018 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Cardiovascular function and structure in heart failure. Cardiovascular structure and function was measured by 2‐dimensional serial echocardiography at baseline and every 2 weeks after acute myocardial infarction for a period of 12 weeks. Left ventricular ejection fraction (LVEF; %; A), left ventricular end‐diastolic diameter (LVEDD; mm; B), left ventricular end‐systolic diameter (LVESD; mm; C), left ventricular end‐diastolic pressure (LVEDP) at 12 weeks (D), and τ at 12 weeks (E). The figure legend indicates treatment groups and number of animals in each group. *P<0.05, **P<0.01 for the difference between valsartan and sacubitril/valsartan (also known as LCZ696).