Table 1.
Treatment |
Blood Gas Parameters |
|||||
---|---|---|---|---|---|---|
Nx/rAIH | ± 2-DG | Tb, °C | , mmHg | , mmHg | pH | MAP, mmHg |
Baseline | ||||||
Nx | − | 37.7 ± 0.1 | 289.1 ± 16.4 | 51.4 ± 0.9 | 7.339 ± 0.006 | 67.2 ± 2.0 |
Nx | + | 37.7 ± 0.1 | 303.8 ± 8.6 | 51.0 ± 0.9 | 7.335 ± 0.005 | 66.8 ± 3.6 |
rAIH | − | 37.9 ± 0.2 | 316.9 ± 4.9 | 51.1 ± 1.2 | 7.316 ± 0.006 | 72.3 ± 2.4 |
rAIH | + | 37.8 ± 0.1 | 286.3 ± 10.9 | 53.3 ± 1.6 | 7.323 ± 0.008 | 75.7 ± 5.2 |
Hypoxia (1st episode) | ||||||
Nx | − | 37.6 ± 0.1 | 44.9 ± 2.2* | 50.6 ± 0.9 | 7.339 ± 0.006 | 39.8 ± 1.6* |
Nx | + | 37.6 ± 0.1 | 44.8 ± 1.3* | 50.3 ± 1.0 | 7.335 ± 0.006 | 43.7 ± 3.1* |
rAIH | − | 37.8 ± 0.1 | 46.1 ± 0.9* | 49.9 ± 1.0 | 7.317 ± 0.009 | 50.4 ± 5.1* |
rAIH | + | 37.7 ± 0.1 | 44.3 ± 1.8* | 51.9 ± 1.3 | 7.329 ± 0.008 | 44.6 ± 3.6* |
60 min | ||||||
Nx | − | 37.9 ± 0.2 | 275.9 ± 6.9 | 50.8 ± 0.8 | 7.341 ± 0.006 | 54.2 ± 2.7* |
Nx | + | 37.9 ± 0.1 | 271.1 ± 8.2* | 50.7 ± 1.0 | 7.335 ± 0.007 | 54.0 ± 3.0* |
rAIH | − | 37.8 ± 0.2 | 279.4 ± 7.3* | 51.6 ± 1.1 | 7.309 ± 0.005 | 52.5 ± 1.8* |
rAIH | + | 38.0 ± 0.1 | 266.0 ± 9.9 | 53.3 ± 1.6 | 7.307 ± 0.011 | 54.3 ± 2.8* |
Values are means ± SE; n = 8 Nx and rAIH + 2-DG and n = 9 Nx + 2-DG and rAIH. Nx, normoxia; rAIH, repetitive acute intermittent hypoxia; 2-DG, 2-deoxy-d-glucose; Tb, body temperature; , arterial Po2; , arterial Pco2; MAP, mean arterial pressure.
Significantly different from baseline (P < 0.05).