Table 3.
Study | α1R/Rα2S/S (WT) MBP, mm Hg | α1R/Rα2R/R MBP, mm Hg | ΔMBP, mm Hg | Reference |
---|---|---|---|---|
1.* | 104.0 ± 2.6 (11)† | 108.2 ± 3.2 (10) | 4.2 | (185) |
2.‡ | 115 ± 3 (8) | 125 ± 5 (10) | 10 | (286) |
3a.§ | 121 ± 8 (4) | 128 ± 3 (5) | 7 | (168) |
3b.§ | 115 ± 6 (5) | 125 ± 4 (7) | 10 | (168) |
4.§ | 97.8 ± 0.8 (7) | 108.2 ± 0.8 (7) | 10.4 | (43) |
Values are means ± SE. WT, wild type; MBP, mean blood pressure.
Mice were “paired for age, weight and sex.”
Numbers of mice shown in parentheses.
Mouse sex not specified. §Male mice; 3a = Experiment no. 1 and 3b = Experiment no. 2. WT, wild type; MBP, mean blood pressure.