Fig. 2.

Cerebral perfusion was restored in bilateral common carotid artery stenosis (BCAS) rats and cerebrovascular reserve capacity was absent in both sham-operated (sham) and BCAS rats. A: BCAS surgery reduced cerebral perfusion, whereas perfusion levels were unchanged with sham surgery. B: at the end of 8 wk, there was no difference in cerebral perfusion between the groups. C: cerebrovascular reserve capacity was absent in both sham stroke-prone spontaneously hypertensive rats (SHRSP) and SHRSP with BCAS. However, 18-wk-old SHRSP had significantly higher reserve capacity compared with 28-wk-old SHRSP. *P < 0.05, different from sham rats; # and ##P < 0.05 vs. 18-wk-old SHRSP.