Table 3.

Relationships between metabolic parameters and postprandial changes in intramyocellular ceramide concentrations

	Fasting Insulin		Postprandial Insulin		HDL-Chol
	ρ	P value	ρ	P value	ρ	P value
IMF fraction
ΔTotal Cer	−0.221	0.188	−0.268	0.109	0.285	0.087
ΔC14:0 Cer	−0.289	0.083	−0.307	0.065	0.007	0.968
ΔC16:0 Cer	−0.257	0.125	−0.222	0.186	0.188	0.264
ΔC18:1 Cer	−0.231	0.169	−0.241	0.151	0.014	0.934
ΔC18:0 Cer	−0.023	0.894	−0.083	0.627	0.174	0.304
ΔC20:0 Cer	−0.069	0.686	−0.093	0.582	0.350	0.034
ΔC24:1 Cer	−0.174	0.304	−0.261	0.119	0.332	0.044
ΔC24:0 Cer	−0.196	0.246	−0.270	0.106	0.395	0.0155
SS fraction
ΔTotal Cer	−0.416	0.010	−0.529	0.0008	0.269	0.107
ΔC14:0 Cer	−0.142	0.401	−0.077	0.649	−0.287	0.085
ΔC16:0 Cer	−0.272	0.104	−0.190	0.259	0.012	0.946
ΔC18:1 Cer	0.116	0.493	0.088	0.603	−0.369	0.025
ΔC18:0 Cer	−0.132	0.435	−0.085	0.615	−0.085	0.617
ΔC20:0 Cer	−0.187	0.269	−0.162	0.338	0.163	0.335
ΔC24:1 Cer	−0.329	0.047	−0.463	0.0039a	0.434	0.0072a
ΔC24:0 Cer	−0.430	0.0078a	−0.553	0.0004a	0.376	0.022

ρ represents the Spearman’s rank correlation coefficient. Intramyocellular ceramides are normalized to mg protein. The change (Δ) in intramyocellular ceramide concentrations was calculated as the data from the second biopsy minus that from the first biopsy.

^aStatistically significant association after modified adjustment for multiple species comparisons.