Table 3.
Summary of changes in urine metabolite concentrations following IRI to the kidney
| Increased | Decreased | Absent | |
|---|---|---|---|
| Alanine | Creatinine | 1- Methyl-nicotinamide | (13/17)a |
| Lactate | Creatinine phosphate | 2-Oxoglutarate | (15/17) |
| Valine | Malonate | 2-Oxoisocaproate | (13/17) |
| Leucine | Nicotinomide-n-oxide | Hippurate | (7/17) |
| Glucose | N-nitrosodimethylamine | Guanine | (5/17) |
| Putrescine | |||
| Dimethyl sulfone* | Sarcosine | ||
| Taurine | |||
| Trigonelline | |||
| Trimethlyamine N-oxide | |||
| Uracil | |||
| Cis-aconitate | |||
| Galactaric acid | |||
| Succinate | |||
| Dimethylamine** | |||
| Fumaric acid* | |||
| Methylamine** | |||
| Methylguanidine** | |||
| Threo isocitric acid** | |||
| Indoxyl sulfate** |
a
The first number indicates the number of spectra in which the metabolite was absent, and the second number indicates the total number of spectra measured.
*
Confirmed using COLMAR with minimal overlap.
**
Confirmed using COLMAR with significant overlap.