Fig. 3.

Application of isradipine does not directly alter K-ATP channel activation. A: representative example for ATP washout current after performing whole cell configuration. Steady-state current is reached after ~20 min of recording; bath application of 300 nM isradipine does not change current amplitude; 2 min after 100 μM tolbutamide bath application washout current is completely blocked. B: isradipine does not significantly change ATP washout current; after tolbutamide application washout current is significantly reduced (n = 4).