Table 1.
Ion channels | |
Fast sodium (Na) | m∞Na = {1 + exp[−(V + 34)/7.8]}−1 |
τmNa = 0 ms | |
h∞Na = {1 + exp[(V + 55)/7]}−1 | |
τhNa = 10/{exp[(V + 50)/15] + exp[−(V + 50)/16]} ms | |
ḡNa = 500 nS | |
Persistent sodium (NaP) | m∞NaP = {1 + exp[−(V + 40)/6]}−1 |
τmNaP = 0 ms | |
h∞NaP = {1 + exp[(V + 55)/12]}−1 | |
τhNaP = 4,000/cosh[(V + 55)/24] ms | |
ḡNaP = 5 nS | |
Potassium rectifier (K) | m∞K = {1 + exp[−(V + 28)/4]}−1 |
τmK = 3.5/cosh[(V + 40)/40] ms | |
ḡK = 40 nS | |
Leak (L) | gL = 2.8 nS |
Neuron parameters | |
Reversal potentials | ENa = 50 mV; EK = −80 mV; ESynI = −75 mV |
Population model: ESynE = −10 mV; EL = −65 ± 0.325 mV | |
Reduced model: ESynE = 0 mV; EL = −62.5 mV | |
Membrane capacitance | C = 20 pF |
Synaptic/network parameters | |
Synaptic parameters | Population model ḡE = ḡI = 0.1 nS; τSynE = τSynI = 5 ms |
Reduced model: ḡSynE = ḡSynI = 1 nS; θ = 25 mV; σ = 5 mV | |
Synaptic connections | Population model (wji = w̄ji ± SD): |
F to F: 0.075 ± 0.00375, p = 0.1 | |
F to In-F: 0.175 ± 0.00875, p = 1 | |
E to E: 0.075 ± 0.00375, p = 0.1 | |
E to In-E: 0.175 ± 0.00875, p = 1 | |
In-F to E: 0.05 ± 0.005, p = 1 (α-E = 5) | |
In-E to F: 0.05 ± 0.005, p = 1 (α-F = 5) | |
Reduced model: α-F = α-E = 1 |
Parameter values are identical for the two models unless otherwise indicated. See methods for definitions.