Table 3.

Angiogenic biomarkers tertiles and relative odds of death

Biomarker	N	Tertile 1 aOR	Tertile 2 aOR (95% CI)	Tertile 3 aOR (95% CI)	p-value for trend
Ang-1	70	1.00 (ref)	0.37 (0.09, 1.52)	0.39 (0.09, 1.62)	0.301
Ang-2	70	1.00 (ref)	1.39 (0.26, 7.36)	5.27 (1.15, 24.07)	0.061
Ang 2:1 ratio	70	1.00 (ref)	0.57 (0.09, 3.54)	4.82 (1.22, 19.03)	0.013
sICAM	70	1.00 (ref)	0.50 (0.09, 2.75)	2.43 (0.60, 9.90)	0.116
sVCAM	70	1.00 (ref)	0.95 (0.22, 4.11)	1.40 (0.36, 5.45)	0.834

aOR adjusted odds ratio, CI confidence interval, Ang-1 angiopoietin-1, Ang-2 angiopoietin-2, Ang2:1 ratio of Ang-2 to Ang-1, sICAM soluble intercellular adhesion molecule-1, sVCAM soluble vascular adhesion molecule-1. P-value for trend using conditional logistic regression adjusted for sex, lethargy and prior antibiotic exposure

Comparisons with p-value less than or equal to 0.05 marked in bold and 0.05–0.10 marked in italics