Fig. 5.

Adhesion of SRRP₅₃₆₀₈-BR to GI tissue. (A and B) Immunostaining pattern for SRRP₅₃₆₀₈-BR on cryosections of mouse colon (A) and stomach (B) correlates with WGA lectin staining. (C) SRRP₅₃₆₀₈-BR binding to mouse colonic sections following sodium periodate treatment at pH 4.5 is significantly reduced. (D and E) SRRP₅₃₆₀₈-BR binds to epithelial cells HT29 (D) and mucus-producing HT29-MTX cells (E). The immunostaining pattern for SRRP₅₃₆₀₈-BR on HT29-MTX cells correlates with WGA lectin staining and partly with anti-MUC5AC staining. Cell nuclei of tissue sections were counterstained with DAPI. (Scale bars: 50 µm.)