Fig. 4.

Gradients of cortical expansion and folding are consistent across subjects. (A) Correspondence between individual surfaces (closest to 30 wk, black arrow) and the 30-wk atlas was determined by aMSM registration. Using intrasubject correspondence from aMSM (double arrows), individual growth patterns from each period were registered to the 30-wk atlas for intersubject statistics. (B) For the period from 30 wk to 38 wk PMA (black double arrow in A), relative area expansion (Top) and regional folding (Bottom) were highest in the lateral parietal–temporal–occipital region and lateral frontal lobe (n = 20). Black and white contours enclose regions where relative expansion is significantly higher and lower than the global average.