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. 2018 Feb 26;115(12):2866–2872. doi: 10.1073/pnas.1721033115

Fig. 5.

Fig. 5.

Cellular signaling networks. Cellular signaling receptors differ in their mechanisms of activation and signal transmission, subcellular localization, and ligand binding (37). Interconnected signaling pathways converge on common effector molecules, which modulate gene expression, mitochondrial functionality, and cytoskeletal structure. Adapted with permission from ref. 37.