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. 2018 Mar 5;115(12):3078–3083. doi: 10.1073/pnas.1721159115

Fig. 2.

Fig. 2.

Description of the monthly distribution of cases within the year per state. (A) Mean timing of cases of nonpolio enterovirus (np-EVs; red) and poliomyelitis (Polio; blue) per state as a function of the latitude of its capital city. The 95% CIs of the mean were obtained by bootstrapping 1,000 times. (B) SD of the timing of cases per state as a function of the latitude of its capital city. In A and B, the lines are cubic splines weighted by the total number of cases reported in each state. The size of the points in B indicates the number of total cases in each state. A sensitivity analysis of A and B data using the latitude of the state’s center of population showed a similar pattern (SI Appendix, Fig. S5). (C and D) US maps showing the mean timing of cases per state. (E–H) Monthly distribution of cases of enterovirus (red) and poliomyelitis (blue) within the year in four different states: California (CA), Florida (FL), Iowa (IA), and New York (NY). In E–H, the vertical lines indicate the estimated mean timing of cases in each state.